1919 - Cholera epidemic hit Agusan area. During this time, Dr. Manuel “Maning” J. Santos was resident doctor of Butuan Hospital.
1933 - The Santos Clinic opened. It started with 12 beds, with the “baul” which Dr. Santos and wife Amparo(Lopez) brought when they first came to Butuan, as one of the furniture in the newly established clinic. It also served as a sitting bench for clients and as side table for patients being examined. At the end of the year, the clinic added 6 more beds to serve the patients. This showed Dr. Santos' growing medical practice.
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